E7449 200mLE7449 is an orally bioavailable, brain penetrable, small molecule dual inhibitor of PARP1 2 and also inhibits PARP5a 5b, otherwise known as tankyrase1 and 2 (TNKS1 2), important regulators of canonical Wnt ? catenin signaling. It has IC50 values of 1. 0 and 1. 2 nM for PARP1 and 2, respectively.
Corning These 12mL PYREX® tall form weighing bottles have a 14/10 Standard Taper joint style opening that accepts a closed bottom
Fenamic acid serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs)
Sulfisomidin is a sulfonamide antibacterial
SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist
used primarily on the eye
5) site of the 20S proteasome with IC50 and Ki of 3
is a potent antiparasitic agent
Also inhibits N-acetyltransferase
8820 and 8825 are used to connect flasks with different size joints
Pilaralisib (XL147) is a selective and reversible class I PI3K inhibitor for PI3K
and selective P2X7 receptor antagonist with pIC50 of 6
Corning These dishes have an approximate working capacity of 1600mL and are designed for use as drying